TMates Review 2026
Reviewed August 7, 2026 · Compounded semaglutide, injectable and oral. Not FDA-approved.
Visit TMates WebsiteOverview
TMates sells compounded semaglutide with the clearest pricing structure we have seen in this directory. It publishes the full ladder — $249 for one month, $217/month on three, $175/month on six and $158/month on twelve, with the total for each term shown alongside the monthly figure and the percentage saved. More importantly, it states that all dosage options carry the same price, and it lists them explicitly: 0.25mg, 0.5mg, 1mg, 1.7mg and 2.4mg. That matters more than the headline number. Dose-banded pricing is the single most common way a cheap GLP-1 programme becomes an expensive one, because the therapeutic dose is usually several steps above the starting dose — a provider quoting $150 at 0.25mg and $400 at 2.4mg is quoting a number you will not pay for long. TMates removes that entirely and says so in its own words: 'Pricing stays consistent across dosage levels, so there's no pressure as your plan adjusts.' It also does something unusually straightforward on safety: its product page lists the likely side effects — nausea, typically subsiding after two to four weeks, mild injection site reactions, decreased appetite, gastrointestinal discomfort — rather than confining them to a linked disclaimer. And it frames outcomes conservatively, saying patients have been seen to lose 'up to 15% of their body weight in a year or less' with the explicit caveat that there is no one-size-fits-all answer.
Medications Offered
Brand-name or compounded: Compounded semaglutide, injectable and oral. Not FDA-approved.
- Compounded semaglutide injectable — once weekly
- Compounded semaglutide oral — daily alternative format
- Dosages 0.25mg, 0.5mg, 1mg, 1.7mg and 2.4mg, all at the same price
- 1 month $249; 3 months $217/mo ($650); 6 months $175/mo ($1,050); 12 months $158/mo ($1,900)
- Medication, provider review, personalised dosing and ongoing support included
- No brand-name or FDA-approved option offered
Consultation Process
Online intake
You complete a short intake covering health history and goals.
Licensed provider review
A licensed medical provider reviews your information before anything is dispensed.
Approval and personalised dosing
If approved you receive a personalised dosing plan. Because all doses cost the same, the clinical decision about dose is not entangled with a pricing decision.
Delivery and ongoing support
Medication is delivered directly with free shipping, and ongoing support continues through TMates. Cancel anytime is stated.
Eligibility
- Adults; no published BMI threshold or age range
- Licensed provider review required before dispensing
- No insurance required — cash-pay
- State availability is not published
- Standard GLP-1 contraindications apply
Provider Involvement
Provider review is required before dispensing and ongoing support is included in the plan price rather than billed separately. TMates also states its physicians monitor progress and notes that most side effects are mild and temporary — framing that treats the clinician as part of the ongoing programme rather than a one-time gate. What is not published is named clinical leadership, a monitoring cadence or any laboratory requirement.
Lab Requirements
Not published. Ask what baseline and ongoing monitoring is expected before starting.
Pharmacy Fulfillment
Not named. TMates does not identify its compounding pharmacy or state its 503A or 503B status. Ask which facility compounds your medication before ordering.
Shipping Frequency
Free shipping direct to your door. Cadence follows the plan term purchased.
Membership Fees vs. Medication Fees
Membership fees
None separate. The plan price covers medication, provider review, personalised dosing and ongoing support.
Medication fees
- 1 month: $249
- 3 months: $217/month, $650 total (save 13%)
- 6 months: $175/month, $1,050 total (save 30%)
- 12 months: $158/month, $1,900 total (save 37%)
- All dosages the same price; medication and support included; free shipping
Cancellation & Refund Policy
Cancellation
TMates states cancel anytime. Note the tension with prepaid plans: the $158/month rate requires $1,900 paid upfront for twelve months, so establish in writing what cancelling means for a prepaid term and whether any refund is prorated at the plan rate or repriced at the monthly rate.
Refunds
Not published beyond the cancel-anytime statement. Ask before committing to a prepaid term.
Insurance
Not offered. TMates is cash-pay and compounded only. If you have GLP-1 coverage, a brand-name provider will almost certainly cost less.
HSA / FSA
Not stated on the pages we rendered. Confirm directly.
See our GLP-1 insurance and HSA/FSA guide for how reimbursement works in practice.
Support Services
- Ongoing provider support included
- Personalised dosing plan
- Free shipping
- Cancel anytime
- Published side effect information on the product page
State Availability
Not published. Confirm your state before starting.
Pros
- All dosage options at the same price — titration never raises your bill
- Complete plan ladder published: $249 monthly down to $158/month on twelve
- Lists likely side effects openly on the product page, including expected timescale
- Injectable and oral formats offered at the same plan pricing
- Medication, provider review and ongoing support included with free shipping
- Cancel anytime; realistic framing of 'up to 15% in a year or less'
Cons
- Compounded only — no brand-name or FDA-approved route
- The best rate requires a $1,900 twelve-month prepayment
- Oral semaglutide has no approved compounded equivalent and no absorption data
- No named compounding pharmacy, published state list or lab requirements
- No published refund policy beyond cancel-anytime
- '2,400+ patients' is a modest base and not externally verifiable
Who TMates May Be Best For
- Cash-pay patients who expect to titrate to a therapeutic dose and want the price to hold
- People who want to see the full cost of every plan length before choosing
- Anyone who values knowing the side effects before rather than after purchase
Limitations
- Compounded only, with no approved or insurance route
- Best rate needs $1,900 upfront
- Oral semaglutide has no approved compounded equivalent
- No named pharmacy, state list, labs or refund policy
Reputation & Trust
TMates gets the two things right that matter most in the mechanics of a compounded GLP-1 programme, and states both plainly. The first is dose-independent pricing. It lists every dosage — 0.25mg through 2.4mg — and confirms they all cost the same, which removes the escalation trap that turns cheap headline rates into expensive maintenance bills across much of this market. Its own explanation is better than most reviewers manage: 'Pricing stays consistent across dosage levels, so there's no pressure as your plan adjusts.' The second is transparent term pricing: the full ladder is published with monthly rate, total cost and percentage saved for each of four plan lengths, so there is nothing to discover at checkout. It also lists likely side effects openly on the product page with expected timescales rather than burying them, and frames outcomes as 'up to 15% of body weight in a year or less' with an explicit no-one-size-fits-all caveat — conservative next to the 20% and 96.8% claims we found elsewhere in this round. The limitations are the ordinary ones for a compounded-only provider: no approved route, no named pharmacy, no state list, no lab requirements, no refund policy beyond cancel-anytime, and a modest claimed base of 2,400+ patients. The oral format also carries the standing problem that no approved compounded oral semaglutide equivalent exists.
What Makes TMates Different
- Every dosage priced identically, with the doses listed explicitly
- Full plan ladder published with monthly rate, total and saving
- Side effects listed openly on the product page with timescales
- Conservative, caveated outcome framing
- Injectable and oral formats at the same plan pricing
Our Verdict
TMates earns 4/5 for having the clearest pricing structure in this directory and for being straightforward about the things providers usually soften. It publishes the complete plan ladder — $249 for one month, $217 on three, $175 on six, $158 on twelve — with the total cost and percentage saved for each, so nothing waits to be discovered at checkout. More valuable still, it lists every dosage from 0.25mg to 2.4mg and confirms they all cost the same, which eliminates the escalation trap that turns cheap headline rates into expensive maintenance bills across much of this market. Its own phrasing is better than most reviewers manage: pricing stays consistent 'so there's no pressure as your plan adjusts'. It also lists likely side effects openly on the product page with expected timescales rather than hiding them behind a disclaimer, and frames outcomes conservatively at 'up to 15% in a year or less' with an explicit caveat — a marked contrast with the 20% body-weight and 96.8% success claims found elsewhere in this round. The limits are the standard compounded-only ones: no approved route, no named pharmacy, no state list, no labs, and a $1,900 upfront commitment for the best rate with no published refund terms. Ask about early exit, then this is a well-built option.
Alternatives to TMates
Also one price for all doses, and with no subscription at all.
Flat dose-independent pricing from $69 with published cancellation contacts.
Brand-name options and the clearest efficacy disclosure in this directory.
Higher priced, but offers FDA-approved pill options and a 90-day guarantee.
Compare more options on our best online GLP-1 providers and cheapest GLP-1 programs pages.
Frequently Asked Questions
Does the price really stay the same as my dose increases?
That is what TMates states, and it lists the doses explicitly — 0.25mg, 0.5mg, 1mg, 1.7mg and 2.4mg — all at the same price. This matters more than the headline number. Most people need several dose increases to reach a therapeutic level, and providers who price by dose can more than double your bill along the way. TMates says it directly: 'Pricing stays consistent across dosage levels, so there's no pressure as your plan adjusts.' Get it confirmed in writing at signup.
What does each plan actually cost in total?
TMates publishes all of it, which is unusual. One month is $249. Three months is $217/month, $650 total. Six months is $175/month, $1,050 total. Twelve months is $158/month, $1,900 total. The savings are stated as 13%, 30% and 37% respectively. Note the cheapest per-month rate requires paying $1,900 upfront, and no refund policy for prepaid terms is published — ask what cancelling means before committing.
Is the oral version worth choosing?
We would default to the injection. There is no FDA-approved compounded oral semaglutide equivalent, so no approved comparator exists and absorption and bioavailability by that route are not established for a compounded formulation. The injectable at least mirrors the route used in the trials that established semaglutide works. If you strongly prefer oral, an FDA-approved option like the Wegovy Pill or Rybelsus — available through other providers in this directory — has far better evidence behind it.
Is TMates' medication FDA-approved?
No. TMates sells compounded semaglutide, which is not FDA-approved, has not been evaluated for safety, efficacy or quality, and is not therapeutically equivalent to Wegovy or Ozempic beyond the shared active ingredient. There is no brand-name option here.
Important Notes & Warnings
- This review is informational only and is not medical advice. Consult a licensed clinician before starting or changing treatment.
- Compounded semaglutide is NOT FDA-approved and is not therapeutically equivalent to Wegovy or Ozempic beyond the shared active ingredient.
- Compounded oral semaglutide has no FDA-approved equivalent and no established absorption or effectiveness data.
- The lowest monthly rate requires $1,900 paid upfront for twelve months, and no refund policy for prepaid plans is published. Get the early-exit terms in writing.
- No compounding pharmacy is named — ask which facility fills your prescription and confirm its 503A status.
- GLP-1 medicines are contraindicated in people with a personal or family history of medullary thyroid carcinoma or MEN2, and in pregnancy.
- Common side effects include nausea, vomiting, diarrhoea, constipation and abdominal pain; serious risks include pancreatitis, gallbladder disease and kidney injury from dehydration.
- TMates notes nausea typically subsides after two to four weeks — but persistent or severe symptoms should go to your prescriber, not be waited out.
Sources
- TMates semaglutide product page and pricing, tmates.com (rendered via headless browser and accessed 7 August 2026 — the site is client-rendered and returns no server HTML)
Medical Disclaimer
This review is for informational purposes only and is not medical advice, a diagnosis, or a treatment recommendation. GLP-1 medications are prescription drugs with real risks and contraindications. Only a licensed clinician who has evaluated you can decide whether any medication is appropriate. Talk to a healthcare provider before starting, changing, or stopping any treatment, and call emergency services for urgent symptoms.
Facts in this review were compiled from the provider's own public website and public search results as of August 7, 2026. Prices, medication availability, pharmacy partners, and policies change frequently and vary by state — verify everything directly with the provider before purchasing.
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